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24 Oct 2016

Presenting our work: United European Gastroenterology week 2016 in Vienna

Additional benefit of surveillance

This week, Marjolein Greuter travelled2016-10-24-uegw-marjolein to Vienna to present her work on colorectal cancer (CRC) screening at the United European Gastroenterology Week. Her presentation concerned the additional impact of surveillance in a CRC screening setting.

Aim of the study

To reduce the burden of CRC, several countries have implemented a screening programme, often in addition to an already existing surveillance programme. Although there is robust evidence that screening reduces CRC-related mortality, there is only limited evidence regarding the benefit of surveillance, especially in a screening setting. Therefore, in this study, we assessed the additional benefit of surveillance on top of screening.

Optical diagnosis

2016-10-24-uegw-jasperOne of our collaborators, Jasper Vleugels, PhD student from the Amsterdam Medical Center, also presented in Vienna. He used our ASCCA model to evaluate an optical diagnosis strategy in a CRC screening programme.

Aim of the study

After a positive CRC screening test, diagnostic colonoscopy follows during which all detected CRC precursor lesions are removed and submitted for histopathological analyses. However, lesions < 5 mm rarely have malignant characteristics. Therefore, alternative strategies are considered such as optical diagnosis. In this strategy, the histology of colorectal lesions <5 mm is endoscopically assessed. When the endoscopist feels confident in his optical diagnosis, these lesions are discarded without histopathological analysis. This may result in considerable less histopathological analyses and thus, cost-savings.

The results of both studies will soon be submitted to an international scientific journal. Follow our website for updates.

 

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